Chemical constituents and lipoxygenase inhibitory activity of Piper stylosum Miq.

  • W. M. N. H. W. Salleh
  • N. A. Hashim
  • S. Khamis
Keywords: Piperaceae, Piper, Piper stylosum, Lignan, Lipoxygenase

Abstract

ABSTRACT. Chemical constituents and lipoxygenase inhibitory activity of the aerial part of Piper stylosum have been studied. Fractionation and purification of the extracts afforded five lignans, identified as yangambin (1), sesamin (2), syringaresinol (3), pinoresinol (4), and medioresinol (5), together with other constituents; 4-allyl resorcinol, β-sitosterol, β-sitostenone, taraxerol, vanilin, and vanilic acid. The structures of these compounds were established by analysis of their spectral data, as compared to that of reported compounds. The lipoxygenase inhibitory activity of the extracts and isolated lignans were also evaluated.

               

KEY WORDS: Piperaceae, Piper, Piper stylosum, Lignan, Lipoxygenase

 

Bull. Chem. Soc. Ethiop. 2019, 33(3), 587-592.   

DOI: https://dx.doi.org/10.4314/bcse.v33i3.19

Published
2019-11-15
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924