Reaction of propargyltrimethylsilane magnesium bromide with aldimines: synthesis of 1-(alkylamino)-2-(trimethylsilyl)but-3- yne
AbstractDepartment of Chemistry, Faculty of Science, University of Douala, P.O. Box 24157, Douala, Cameroon (Received February 22, 2001; revised May 10, 2002) . The reaction of propargylsilane magnesium bromide with aldimines provides in some cases, an isomeric mixture of three acetylenic amines 1, 2, 3 (1 and 2, as major products). The reaction has great potential and has been exploited for an efficient synthesis of the pure amine 2.
Bull Chem Soc Ethiop (2002) 16(2), 169-174