SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF SOME METAL COMPLEXES WITH THE SCHIFF BASE OF A HETEROCYCLIC ALDEHYDE

  • Aurora Reiss University of Craiova, Faculty of Chemistry, 107I Calea Bucuresti , Romania
  • Theodor Căproiu Institute of Organic Chemistry, 202B Spl. Independentei, 77208, Bucharest, Romania
  • Nicolae Stănică Institute of Physical Chemistry, 202 Spl. Independentei, 77208 Bucharest, Romania
Keywords: Schiff base, Metal complexes, Antibacterial activity

Abstract

Metal complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II) with a new Schiff base derived from 3-aminodibenzofuran and 2-furancarboxaldehyde are reported. The complexes have been characterized using chemical analysis, spectroscopic methods (IR, UV-vis, 1H NMR and ESR), conductometric and magnetic data. According to these data, we propose an octahedral geometry for Co(II), Ni(II) and Cu(II) complexes and a tetrahedral geometry for Zn(II), Cd(II) and Hg(II) complexes. Antibacterial activity of the ligand and its complexes were studied against selected bacteria: Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. It has been found that all the complexes are antimicrobially active and show higher activity than the free ligand.


KEY WORDS: Schiff base, Metal complexes, Antibacterial activity


Bull. Chem. Soc. Ethiop. 2009, 23(1), 63-68.

Published
2009-04-01
Section
Articles

Journal Identifiers


eISSN: 1726-801X
print ISSN: 1011-3924