One step protocol and green synthesis of 2-N,N-dimethylamino-3-alkyl(aryl)-2-oxido-1- hydro-2-benzo[1,3,2]diazaphosphinine-4-one derivatives

Abstract

ABSTRACT. 2-N,N-dimethylamino-2-oxido-3-alkyl(aryl)-1-hydro-2-benzo[1,3,2]diazaphosphinin-4-one (2) derivatives  are synthesized by one pot reaction by reacting equimolar quantities of anthranilic acid, primary amine, and N,N-dimethylphosphoramic dichloride under reflux of ethanol with good yields. The structure of the compounds were established on the basis of their infrared, nuclear magnetic resonance spectral data (¹H NMR, ¹³C NMR and ³¹P NMR), mass spectrometry, and elemental analysis.

KEY WORDS: Anthranilic acid, N,N-Dimethylphosphoramic dichloride, Diazaphosphinine

Bull. Chem. Soc. Ethiop. 2022, 36(4), 859-864.                                                            

DOI: https://dx.doi.org/10.4314/bcse.v36i4.11