Preparation of diethyl malonate adducts from chalcone analogs containing a thienyl ring

  • Yakup Budak
  • M. Burcu Gürdere
  • Meryem Keçeci
  • Mustafa Ceylan
Keywords: Michael addition, Chalcone, KOt-Bu, Diethyl malonate

Abstract

Nine chalcone-diethyl malonate derivatives (4a-i) were prepared by the reaction of chalcone derivatives (3a-i) with diethyl malonate in the presence of a catalytic amount of KOt-Bu in CH2CI2 in good to excellent yields. The products were characterized by FTIR, 1H-NMR, 13C-NMR and elemental analyses.

 

KEY WORDS: Michael addition, Chalcone, KOt-Bu, Diethyl malonate

 

 

Bull. Chem. Soc. Ethiop. 2010, 24(1), 85-91.

 

 

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eISSN: 1726-801X
print ISSN: 1011-3924