<b>Preparation of diethyl malonate adducts from chalcone analogs containing a thienyl ring</b>

Abstract

Nine chalcone-diethyl malonate derivatives (4a-i) were prepared by the reaction of chalcone derivatives (3a-i) with diethyl malonate in the presence of a catalytic amount of KOt-Bu in CH₂CI₂ in good to excellent yields. The products were characterized by FTIR, ¹H-NMR, ¹³C-NMR and elemental analyses.

KEY WORDS: Michael addition, Chalcone, KOt-Bu, Diethyl malonate

Bull. Chem. Soc. Ethiop. 2010, 24(1), 85-91.