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<b>Silica sulfuric acid promoted one-pot synthesis of benzo[4,5]imidazo[1,2-<i>a</i>]pyrimidine derivatives under solvent-free conditions</b>

Liqiang Wu
Fulin Yan
Chunguang Yang


A simple and efficient synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine derivatives has been accomplished by the reaction of 2-aminobenzimidazole, aldehydes and β-dicarbonyl compounds under solvent-free conditions in the presence of silica sulfuric acid.


KEY WORDS: Benzo[4,5]imidazo[1,2-a]pyrimidine, Silica sulfuric acid, 2-Aminobenzimidazole, Aromatic aldehydes, β-Dicarbonyl compounds, Solvent-free


Bull. Chem. Soc. Ethiop. 2010, 24(3), 417-423.

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eISSN: 1726-801X
print ISSN: 1011-3924