PCl5 as a mild and efficient catalyst for the synthesis of bis(indolyl)methanes and di-bis(indolyl)methanes

  • Alireza Hasaninejad Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, Iran
  • Abdolkarim Zare Department of Chemistry, Payame Noor University of Bushehr, Bushehr 1698, Iran
  • Hashem Sharghi Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
  • Reza Khalifeh Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
  • Ahmad Reza Moosavi Zare Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
Keywords: PCl5, bis(Indolyl)methane, di-bis(Indolyl)methane, Indole, Aldehyde, Ketone

Abstract

Phosphorus pentachloride (PCl5) can efficiently catalyze the condensation of indoles with aldehydes as well as ketones at room temperature to afford bis(indolyl)methanes and di-bis(indolyl)methanes in high yields and short reaction times.

 

KEY WORDS: PCl5, bis(Indolyl)methane, di-bis(Indolyl)methane, Indole, Aldehyde, Ketone

 

 

Bull. Chem. Soc. Ethiop. 2008, 22(3), 453-458.

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