Effect of dielectric constant of medium on chemical speciation of L-histidine complexes of Co(II), Ni(II) and Cu(II)

  • Raju Sala
  • Ananda Kumar Bokka
  • Bharath Kumar Naik Kethavath
  • Nageswara Rao Gollapalli

Abstract

Chemical speciation of binary complexes of Co(II), Ni(II) and Cu(II) ions with L-histidine have been studied pH metrically in the concentration range of 0–60% v/v DMSO-water mixtures maintaining an ionic strength of 0.16 M at 303 K. Alkalimetric titrations were carried out in different relative concentrations of metal and histidine. Stability constants of various models of binary complexes were refined with MINIQUAD75. The best-fit chemical models were selected based on statistical parameters and residual analysis. The species detected are MLH, ML­2, ML2H, ML2H2 and ML2H4 for Co(II); ML­2, ML2H, ML2H2 and ML2H4 for Ni(II); and MLH, ML2, ML2H and ML2H2 for Cu(II). The chemical speciation, metal bioavailability and transportation are explained based on the distribution diagrams.

 

KEY WORDS: L-Histidine, Chemical speciation, Essential metals, Binary complexes, Bioavailability, DMSO

 

Bull. Chem. Soc. Ethiop. 2012, 26(2), 227-238.

DOI: http://dx.doi.org/10.4314/bcse.v26i2.6

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eISSN: 1726-801X
print ISSN: 1011-3924