Bulletin of the Chemical Society of Ethiopia

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Quantitative determination of formaldehyde by spectrophotometry utilizing multivariate Curve resolution alternating least squares

Mohammadreza Khanmohammadi, Nasser Dalali, Farshad Karami, Amir Bagheri Garmarudi, Hossein Nemati


Formaldehyde is a vastly used material in industry. Nowadays, it is proven that formaldehyde is toxic and carcinogenic. Thus providing a reliable method for its quantitative determination is very important. This study proposes a UV-Vis spectrophotometric based method for determination of formaldehyde. The method is based on reaction between the analyte and Fluoral P. Spectral changes during the time were mathematically analyzed using a chemometrics technique, called "multivariate curve resolution alternating least squares" (MCR-ALS). Data processing by this chemometrics technique enhanced the reliability of the UV-Vis spectrophotometry for quantitative analysis of formaldehyde in real samples.


KEY WORDS: Formaldehyde, Fluoral P, UV-Visible, Multivariate curve resolution alternating least squares; Quantitative analysis


Bull. Chem. Soc. Ethiop. 2012, 26(2), 299-304.