Synthesis and antimicrobial activity of some new pyrrole derivatives

Abstract

New pyrrole derivatives were synthesized and structures were confirmed by IR, ¹H NMR, ¹³C NMR, mass spectra, and elemental analyses data. The reaction was performed by using ordinary condensation type, which enabled to easy work-up and good yield. Synthesized compounds were screened for antimicrobial activity.

KEY WORDS: Pyrrole, 1,3,4-oxadiazol-2-amine, 4H-1,2,4-triazol-3-ol, Cyclization, Antimicrobial activity, Structure activity relationship

Bull. Chem. Soc. Ethiop. 2012, 26(3), 429-435.

DOI: http://dx.doi.org/10.4314/bcse.v26i3.12