Synthesis and antimicrobial activity of some new pyrrole derivatives

  • A Idhayadhulla
  • R Surendra Kumar
  • AJ Abdul Nasser
  • A Manilal
Keywords: Pyrrole, 1, 3, 4-oxadiazol-2-amine, 4H-1, 2, 4-triazol-3-ol, Cyclization, Antimicrobial activity, Structure activity relationship

Abstract

New pyrrole derivatives were synthesized and structures were confirmed by IR, 1H NMR, 13C NMR, mass spectra, and elemental analyses data. The reaction was performed by using ordinary condensation type, which enabled to easy work-up and good yield. Synthesized compounds were screened for antimicrobial activity.

KEY WORDS: Pyrrole, 1,3,4-oxadiazol-2-amine, 4H-1,2,4-triazol-3-ol, Cyclization, Antimicrobial activity, Structure activity relationship

 

Bull. Chem. Soc. Ethiop. 2012, 26(3), 429-435.

DOI: http://dx.doi.org/10.4314/bcse.v26i3.12

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eISSN: 1726-801X
print ISSN: 1011-3924