Microwave-assisted synthesis of some 5(6)-nitro-1H-benzimidazoles and their hydrazide derivatives

Abstract

A series of 5(6)-nitro-1H-benzimidazole and their hydrazide derivatives were synthesized starting from iminoester hydrochloride and 4-nitro-o-phenylenediamine under microwave irradiation. The structure of all synthesized compounds was confirmed by IR, ¹H-NMR, ¹³C-NMR, ESI-MS spectroscopy and elemental analysis.

KEY WORDS: Benzimidazole, Iminoester hydrochloride, Microwave irradiation, Hydrazine hydrate

Bull. Chem. Soc. Ethiop. 2013, 27(2), 265-271.

DOI: http://dx.doi.org/10.4314/bcse.v27i2.11