Solid State Synthesis, Characterization and Antimicrobial Study of 4,4′- Bipyridinecopper (II) Complexes

Abstract

The state of the art in crystal engineering and mechanochemistry were exploited to synthesize 4,4′-bipyridine copper (II) chloride and 4,4′-bipyridine copper (II) (MOF) by mechanochemical grinding of [4,4′-H₂bipy]Cl₂ with copper(II) acetate and the subsequent grinding of the coordination compound [CuCl₂4,4′-bipy] with an external base (K₂CO₃). The complexes obtained were characterized by elemental analysis, infrared spectral studies, decomposition temperature determination, conductivity measurement and solubility test. The molar conductivity value range from 38.0-40.2 Ω^-1cm² mol^-1, and its decomposition temperature ranges from 171– 189^oC. The elemental analytical data and infrared values indicated that the complexation has taken place. The complexes were effective against some selected bacteria and fungi (escherichia coli, pseudomonas aeruginosa, streptococcus pneumonae, staphylococcus aureus, klebsiella specie and penicillium specie, meterhizium specie, aspergilus species) at 1000μg/disk (highest concentration).

Keywords: 4,4′-bipyridinium chloride, mechanochemistry, metal-organic framework