Lupeol Acetate Isolated from n-Hexane Extract of Tapinanthus globiferus Leaf

  • L.G. Hassan
  • M.G. Liman
  • H.E. Msheila
  • C. Ogbiko
  • A. Babagana
  • O. Andrew
Keywords: Tapinanthus globiferus, Lupeol Acetate, Structure elucidation

Abstract

A study was carried out to isolate and characterise Lupeol Acetate from the leaves of Tapinanthus globiferus. The dried pulverized plant material was extracted for 24 hours with n-hexane, dichloromethane, ethyl acetate and methanol solvents. The /n-hexane fraction obtained was subjected to column chromatography followed by preparative thin layer chromatography, which resulted in isolation of a colourless crystalline compound. The spectral data (1H NMR, 13C NMR and FTIR) and literature comparison infer that the isolated compound is a pentacyclic triterpenoid namely Lupeol Acetate.

Keywords: Tapinanthus globiferus, Lupeol Acetate, Structure elucidation

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eISSN: 2384-6028
print ISSN: 2276-707X