Nodular Lymphangitis in HIV-Infected Patients in Tanzania

Abstract

Data on nodular lymphangitis among HIV-infected patients in Tanzania are scarce. Nodular lymphangitis  defines a clinical presentation with erythematous subcutaneous nodules along the lymphatic channels. Early  diagnosis, biopsy or culture of skin lesions and treatment are essential for improving outcomes. However, this  is challenging in resource-limited settings. We present two HIV-infected patients with nodular lymphangitis treated with ketoconazole in the absence of itraconazole or amphotericin B with good initial response. At the end of treatment, patient no. 2 showed a total resolution of the lesions, but patient no. 1 died after self-withdrawing from treatment at month four.