East African Medical Journal

Log in or Register to get access to full text downloads.

Remember me or Register

DOWNLOAD FULL TEXT Open Access  DOWNLOAD FULL TEXT Subscription or Fee Access

A clinico-pathological evaluation of ovarian teratomas in Uyo, Nigeria during a 10 year period

N.C. Charles, N.N. Nnenna


Objective: To show the clinicopathologic pattern of ovarian teratomas (OT) in Uyo, Nigeria and how they compared to results from other parts of the world.

Design: This was a quantitative observational, descriptive study of all OT specimens that were histologically diagnosed in the Histopathology Department of University of Uyo Teaching Hospital, Uyo, Nigeria.

Results: Of the 149 ovarian specimens received, OT was seen in 54 cases accounting for 36.2% of all ovarian lesions. Most of the patients were between age groups 20-29 years (37%) and 30-39 years (29.6%). The youngest patient was aged 4.5 years, while the oldest was 68 years with a mean age of 33.7 years with a standard deviation of 13.8. The complaints at presentation were mainly abdominal pain (50%), abdominal swelling (42.6%), per vagina bleeding (7.4%). All the patients had laparotomy, which was a cystectomy (68.5%), oophorectomy (22.2%) or a hysterectomy (9.3%). In 46.3% of cases, the widest diameter of the mass was greater than 10cm, while in 37% of cases, the widest diameter was ≤ 10cm. The contents were cheesy material admixed with tuft of hair (70.4%), sebum (37%), serous / mucinous fluid (18.5%), bone (7.4%), teeth (5.6%), cartilage (5.6%). Histologically majority of the OT were mature teratomas (MT) (88.9%). Malignant transformation of a MT (MTMT), immature teratoma and struma ovarii were seen in 5.6%, 3.7% and 1.9% of cases respectively.

Conclusion: The frequency and pattern (histologically) is same as known for OT globally. Very few asymptomatic patients presented, while no patient had laparoscopic surgery.

AJOL African Journals Online