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Case-Control Study Of Risk Factors For Breast Cancer In Nigerian Women: A Pilot Study
Abstract
Objective: To evaluate the risk factors for breast cancer among women in Midwestern and Southeastern Nigeria.
Design: A case control study.
Setting: University of Benin Teaching hospital, Benin City and University of Port Harcourt Teaching Hospital, Port Harcourt in Nigeria.
Subjects: Fifty one women with diagnosis of breast cancer and their age- and sex matched controls were included in the study.
Interventions: Data was collected during a 30 minute period after obtaining written informed consent using interviewer-administered questionnaires.
Results: Parity>4 (OR=0.50, 95% Cl 0.17, 1.46) and duration of breast feeding>60 months (OR=0.58, 95% Cl 0.23, 1.48) were associated with reduced risk of breast cancer while birth order>3 (OR=I.50, 95% Cl 0.25, 8.98), age at first full term pregnancy>20 years (OR=2.50, 95% Cl 0.78, 7.97) and longer duration of reproductive period (OR=1.25, 95% Cl 0.34, 4.66) were associated with increased risk of breast cancer.
Conclusion: The study has shown that high parity and long duration of breastfeeding are associated with reduced risk while high birth order and late age at first full-term pregnancy are associated with increased risk of breast cancer.
East African Medical Journal Vol.82(1) 2005: 14-19
Design: A case control study.
Setting: University of Benin Teaching hospital, Benin City and University of Port Harcourt Teaching Hospital, Port Harcourt in Nigeria.
Subjects: Fifty one women with diagnosis of breast cancer and their age- and sex matched controls were included in the study.
Interventions: Data was collected during a 30 minute period after obtaining written informed consent using interviewer-administered questionnaires.
Results: Parity>4 (OR=0.50, 95% Cl 0.17, 1.46) and duration of breast feeding>60 months (OR=0.58, 95% Cl 0.23, 1.48) were associated with reduced risk of breast cancer while birth order>3 (OR=I.50, 95% Cl 0.25, 8.98), age at first full term pregnancy>20 years (OR=2.50, 95% Cl 0.78, 7.97) and longer duration of reproductive period (OR=1.25, 95% Cl 0.34, 4.66) were associated with increased risk of breast cancer.
Conclusion: The study has shown that high parity and long duration of breastfeeding are associated with reduced risk while high birth order and late age at first full-term pregnancy are associated with increased risk of breast cancer.
East African Medical Journal Vol.82(1) 2005: 14-19
