Primary gastrointestinal lymphoma in immunocompromised patient. Case report and literature review

Abstract

Primary gastrointestinal lymphoma is a rare disease with no specific clinical presentation. Early diagnosis is usually based on suspicious index, otherwise majority of patients present at late with very advanced disease with complications. The incidence of primary gastrointestinal lymphoma is increasing with HIV disease. There are several classification and staging systems with different treatment options varying from one center to another. Prognosis depends on the stage at presentation, degree of differentiation and age. It was concluded that early diagnosis depends on degree of suspicious index with good treatment response. Late presentation is accompanied by marked immunosuppresion. Future research needs to determine whether single or combined modalities of treatment have good treatment outcomes. A case of primary gastrointestinal lymphoma in immunocompromised patient is reported with literature review.