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Compartive study between the effects of human CD34 and rat bone marrow mesenchymal stem cells on amelioration of CCL4 induced liver fibrosis


Amany O Mohamed
Naglaa K Idriss
Dina Sabry
Mona Magdy
Hayam G Sayyed
Azza S Abdelrhim

Abstract

Human umbilical cord blood (UCB) cells and rat bone marrow mesenchymal stem cells (BM-MSCs) have many advantages as grafts for cell transplantation. The aim of this study was to investigate the impact of UCB cells and BM-MSCs on reversal of hepatic injury and revival of hepatic function in a rat model of carbon tetrachloride
(CCl4)-induced liver fibrosis.

 

Keywords: CCl4 liver fibrosis, Umbilical cord blood CD34+  Bone marrow stem cell, Stem cell therapy.


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eISSN: 1687-1502