Assessment of the Thyroid Hormones in Patient with Chronic Renal Failure Undergoing Maintenance Haemodialysis in Hospital Cross Section Study

Abstract

Background: A significant alteration in thyroid hormone function tests occurred in chronic kidney disease (CKD) patients especially if  they are on dialysis.

Objective: The purpose of our study was to determine the prevalence of thyroid hormone abnormalities among chronic renal failure  patients undergoing maintenance haemodialysis, and to assess the connection between thyroid hormones dysfunction, duration of  dialysis, complication of chronic renal failure and other comorbidities.

Patients and Methods: This cross-section study was executed on 200 patients exceeding the age of 18, with confirmed end-stage renal  disease (ESRD. Patients were split into 4 groups based on status of thyroid dysfunction into hypothyroidism group, hyperthyroidism  group, normal thyroid or sick euthyroid group.

Results: There was overt hypothyroidism in 20 (64.51%) patients and subclinical  hypothyroidism in 11(5.5 %) patients. However, overt hyperthyroidism was in 9 (4.5%) patients and subclinical hyperthyroidism was in 10  (5 %) patients. Sick euthyroid was found in 83 (41.50%) patients and finally, euthyroid patients was in 67 (33.50%) patients.

Conclusions:  Thyroid hormone dysfunction is common in chronic renal failure patients undergoing maintenance hemodialysis, even in those who are  clinically euthyroid.