Correlations between antibiotic intake and resistance of some enteric gram negative bacilli to antibiotics

Abstract

Some enteric Gram negative bacteria were isolated over a three – year (2006 – 2008) period from two human populations designated as population on therapy (OD) and population not on therapy (ND). Isolates were analyzed for
susceptibility to a panel of ten antibacterial agents. Results showed that OD isolates were generally more resistant to test drugs than ND isolates but the differences were not significant at both 0.01 and 0.05 levels. Pearson correlation analysis showed that the correlation in resistances among the OD and ND isolates was systematic and significant at both 0.01 and 0.05 levels, suggesting that resistance emergence and sustenance may not be an exclusive consequence of intake and misuse of antibiotics.