Spectroscopic studies on Isatin-3-Semicarbazone and Isatin-3-Thiosemicarbazone

Abstract

The configurations of semi-and thiosemicarbazone derivatives of isatin are assigned by means of ¹H and ¹³C NMR Spectroscopy including NOE difference spectra, IR and electronic spectral data of these compounds are also reported and discussed. The electron impact (EI), fast atom bombardment (FAB) and negative ion chemical ionization (NICI) mass spectra are also reported. Fragmentation of molecular and pseudomolecular ions are tabulated and rationalized.


KEY WORDS: ^IH NMR, ¹³C NMR, Semicarbazone thiosemicarbazone, mass spectra, negative ion chemical ionization, fragmentation.


Global Jnl Pure and Applied Sciences Vol.10(4) 2004: 545-553