Determinants of viral load non-suppression among people living with HIV on antiretroviral therapy in Kumasi, Ghana

  • David KO Ansah Faculty of Health and Allied Sciences, Catholic University College of Ghana, P.O. Box 363, Fiapre –Sunyani
  • Emmanuel Kumah Policy, Planning, Monitoring & Evaluation Unit, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
  • Vitalis Bawontuo Faculty of Health and Allied Sciences, Catholic University College of Ghana, P.O. Box 363, Fiapre –Sunyani
  • Peter Agyei-Baffour Department of Health Policy, Management and Economics, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
  • Emmanuel K Afriyie Laboratory Services Directorate, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
Keywords: HIV/AIDS, anti-retroviral therapy, viral load suppression, virological failure, Ghana

Abstract

Objectives: To determine the rate and factors associated with viral load non-suppression among adults living with HIV/AIDS on active anti-retroviral therapy (ART).
Design: A retrospective cross-sectional study
Setting: Three ART clinics in Kumasi, Ghana
Participants: All HIV-infected adults who were ≥18 years and on active ART for 12 months and whose viral loadnhad been estimated were included.
Main outcome measure: Unsuppressed viral load among patients on ART
Results: In all, 483 HIV patients were included in the study, with 369 (76.4%) achieving viral load suppression. Gender, educational level, comorbidity status, and duration on ART were independently associated with viral nonsuppression (p < 0.05).
Conclusions: This study has revealed that the rate of viral suppression in the study area is lower than the UNAIDS 90% target. The findings have implications on designing new and stemming up implementation of existing interventions to improve the rate of viral suppression among patients in the study area. It is also necessary that more of such studies are replicated in other parts of the country to identify risk factors for virological failure among patients on ART.

Published
2021-06-01
Section
Articles

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print ISSN: 0016-9560