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Feb 8, 2016Keywords:
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Effect of ageing on some biophysical parameters amongst males in Benin City, Nigeria
Abstract
This study was designed to assess the effect of ageing on the CD4+ T cells count, testosterone, progesterone, and estrogen concentration in a view to evaluating the alterations associated with it. A total of 102 subjects aged between 20 and 80 years participated in the study.CD4+ T cell was estimated using Partec cyflow counter. Testosterone, progesterone and estrogen were determined by enzyme-linked immunosorbent assay methods. Our finding revealed a significant decrease in absolute lymphocyte count, CD4+ T cells count, progesterone, and testosterone concentration of the elderly males when compared with the young males (P < 0.05). Ageing induces a decrease in CD4+ T cells, progesterone and testosterone level which could be linked to the complications associated it.
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Keywords: CD4+ T cells, ageing, testosterone, hypogonadism, thymus gland
