Effect of chia seeds (<i>Salvia hispanica</i>) on postprandial glycaemia, body weight and hematological parameters in rats fed a high fat and fructose diet

Abstract

Chia seeds (Salvia hispanica) are currently consumed by varied populations as superfoods due to their protective, functional and antioxidant properties. The aim of this study was to determine the effect of ground chia seeds/extracts on postprandial glycaemia, body weight, hematological parameters and cellular morphology in rats. Twenty male Wistar rats were assigned into three experimental groups and a control (n =5). Each experimental group received 10 g/20 g fructose/lard. Additionally, 90 g rat pellet was fed to group 1 and 3 which was supplemented with 20 g chia seed extract, group 2 received ground chia seeds only. Control group received 90 g rat pellet only for 28 days. The results on body weight changes indicated a gradual increase in body weight of chia seeds/extract fed rats as compared to fructose/lard group. There was an increase in postprandial blood glucose levels in group 1 from week I to IV contrary to groups supplemented with chia seeds/extract. Complete blood counts showed a significant increase (p = 0.008) in mean corpuscular hemoglobin concentration, basophils (p = 0.035), platelets (p = 0.025) and red cell distribution width (p = 0.008) in experimental groups compared to control. These results pinpoint the benefits of chia seeds.

Keywords: Blood composition, functional food, glucose concentration, metabolic diseases, omega-3 fatty acids