Synthesis of novel pyrido- and pyrimidino-[2\',1\':2,3][1,3] thiazolo [4,5-B] quinoxalines.

Craig A Obafemi; Wolfgang Pfleiderer

doi:10.4314/ijs.v6i1.32118

Craig A Obafemi Department of Chemistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
Wolfgang Pfleiderer Fachbereich Chemie, Konstanz University, D-78457 Konstanz, Germany

DOI: 10.4314/ijs.v6i1.32118

Abstract

New pyrido- and pyrimidino[2\',1\':2,3][1,3] thiazolo[4,5-b] quinoxalin-12-ium salts 7 could be synthesized from cyclizations of 2,3-dichloroquinoxalines with 2-mercaptopyridine and 2-mercaptopyrimidine, respectively. The pyrimidino- thiazoloquinoxaline 7d reacts further with acetyl-compounds to afford the corresponding 1-(acylmethyl)-1H-pyrimidino[2\',1\':2,3][1,3] thiazolo[4,5-b]quinoxalines, 9.
Ife Journal of Science Vol.6(1) 2004: 23-29

Synthesis of novel pyrido- and pyrimidino-[2\',1\':2,3][1,3] thiazolo [4,5-B] quinoxalines.

Abstract

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