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SARS-CoV-2 is a highly transmissible and pathogenic viral infection. Its global spread has a profound effect on the lives of millions of people resulting to worldwide economic disruptions and increased death tolls. This has created fears and concerns within the health sector globally. Thus, understanding the mode of transmissions, aetiology, pathogenesis, environmental conditions and epidemiology of SARS-CoV-2 will help in curbing and militating against further spread of the virus. It has also become imperative to look out for petty openings through which this virus may invade man's territories by nature or man-made via negligence. There is need for regular water treatment to prevent further spread that may undoubtedly predispose humans to COVID-19 in the long run as lakes often serve as the only source of drinkable water in rural communities particularly in developing countries. It is against this backdrop that we intended to investigate possible means of SARS-CoV-2 invasion in water bodies in support of the global fight against COVID-19 with a particular focus on lakes. Therefore, this article emphasizes on possible transmissions of SARS-CoV-2 from lakes and provided remedies in support of the views of some researchers that appeared to be inconclusive.