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Toxicological evaluation of methanol extract of <i>Khaya senegalensis</i> leaves in African catfish <i>Clarias gariepinus</i>


OA Abui
MM Motouke

Abstract

The toxicity of methanol extract of Khaya senegalensis leaves was evaluated in Clarias gariepinus over 96 h exposure. The fish were exposed to 150 mg/L. 170 mg/L. 190mg/L, 210 mg/L and 230 mg/L of the extract and a control in acute static bioassay after a trial finding to determine the median lethal concentration (LC50) of the extract. Exposed fish showed clinical signs, such a distress opercula ventilation, tail fin beats and  respiratory alteration. The frequency of opercula ventilation and tail fin beats were concentration dependent and showed significant association (P<0.05). The LC50 value of 199,69mg/L was established for the extract in the exposed fish where mean mortally was significantly (P<0.05) concentration and exposure dependent. This plant is to be regarded as a piscine toxicant and should be discarded from the bank of rivers and dams.

Keywords: Acute effect, Histopathology, Khaya senegalensis, Clarias gariepinus


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eISSN: 2659-1499
print ISSN: 2659-1502