The Chemical Constituents and Bioactivity of the seed (Fruit) extracts of <i>Buchholzia Coriacea</i> Engler (Capparaceae)

Abstract

Buchholzia coriacea Engler (Capparaceae) is important in traditional medicine because many parts of the plant have been reported to possess therapeutic potentials. The seeds of the fruits of Buchholzia coriacea were extracted with petroleum ether, chloroform and methanol respectively, and the crude extracts were analyzed using GC-MS. The result indicated presence of cyclooctasulphur, oleic acid, (Z,Z)-9,12-octadecadienoic acid, nhexadecanoic acid, methyl ester (Z,Z)-9,12 octadecadienoic acid, 5-hydromethylfurfural, (E)- 9-octadecanoic acid, 1-methyl pyriolidine-2-carboxylic acid, undecane, palmitoleic acid, stigmasterol, beta-sitosterol and methyl ester 3,5-dicyclohexyl-4-hydroxy-benzoic acid amongst other constituents. Bioactive test of the crude extracts and fractions from column chromatography showed great potential as antifungal agent than antibacterial agent, when tested against isolated fungi and Gram-positive and Gram-negative bacteria.

Keywords: Buchholzia coriacea, Capparaceae, antifungal activity, bioactivity, chemical constituents, fruits