Isolation, characterization and antimicrobial study of lupeol acetate from the root bark of Fig-Mulberry Sycamore (<i>Ficus sycomorus</i> LINN)

Abstract

The phytochemical investigation of n-butanolic extract from the root bark of Ficus sycomorus using microwave-assisted extraction revealed the presence of steroids, triterpenes, flavonoids, alkaloids, and tannins. Detailed chromatographic techniques on the extract led to the isolation of a triterpenoid compound for the first time from the part of the plant, which was identified as lupeol acetate by chemical and spectroscopic studies. Antimicrobial activity study of the isolated compound on some selected microorganisms showed that the compound is a potential source of antibiotic agents.

Keywords: Antimicrobial, Ficus sycomorus, lupeol acetate, root bark