Assessment of Antimicrobial Effect of Alcohol and Aqueous Extracts of <i>Garcinia kola </i>on <i>Staphylococcus aureus</i>, Bacillus cereus, Escherichia coli</i> and<i> Klebsiella pneumonia</i>

Abstract

As a result of the development of resistance of microorganisms to older antimicrobial agents there is need for a search for new agents, which are effective for the treatment of infections. The crude aqueous and alcoholic extr acts of Garcinia kola fruits were assayed against Staphylococcus aureus, Bacillus cereus, Escherichia coli and Klebsiella pneumoniae. The results revealed that the plant extracts possess inhibitory effect against the microorganisms tested. The minimum inhibitory concentration of the plant extracts ranged between 20mg/ml and 45mg/ml. There was a change in the antibacterial activity of the test extracts on variation of temperature. The results obtained may suggest that the plant extract is thermal stable and could serve as a source of industrial drugs useful in chemotherapy of some microbial infections.

Keywords: Garcinia kola, microorganisms, inhibitory, chemotherapy, drug