Journal of Medical Investigation and Practice 2022-05-19T07:48:20+00:00 Prof. Stephen Onwere Open Journal Systems <p>The Journal of Medical Investigation and Practice (JOMIP) is a quarterly peer-reviewed international journal published by the College of Medicine and Health Sciences, Abia State University. The journal's full text is available online at <a href="" target="_blank" rel="noopener"></a>. The journal allows free access to its contents and permits authors to self-archive final accepted version of the articles on any OAI complaint institutional/ subject-based repository. The journal makes a token charge for submission, processing and publication of manuscripts including colour reproduction of photographs.</p> Intradialysis complications of Haemodialysis: Experience from two kidney centres in Aba, South-East, Nigeria. 2022-05-19T07:35:54+00:00 UN Onwuchekwa MO Nkpozi JO Ehiemere <p>Despite advances in haemodialysis (HD) machine technology and improvement in dialysis water purification and quality of dialyzer membranes, complications still occur during HD. There is a paucity of published literature on intradialysis complications in Aba, Southeast Nigeria. This study, therefore, set out to bridge this gap in knowledge. This was a 5-year observational study in which patients that had HD sessions in Living Word Ministry Hospital (LWMH) and Abia State<br>University Teaching Hospital (ABSUTH), Aba were consecutively recruited. This study lasted from January 1, 2015 to March 31, 2020. Relevant data comprising patient's demographics and the complications suffered during the HD sessions were analyzed using Statistical Package for Social Sciences (SPSS) version 23.0 software. A total of 188 patients who had 880 HD sessions participated in the study in which intradialysis complications occurred in 18.6% of the sessions. More males than females participated and had more complications while the predominant complications noted were hypotension followed by rigor and vomiting. It is recommended that efforts should be put in place to achieve early detection and treatment of intradialysis complications of HD without terminating the dialysis procedure.</p> 2022-05-19T00:00:00+00:00 Copyright (c) Assessment of barriers to HIV Screening among adolescents in Girls Secondary School, Abayi, Aba. 2022-05-19T07:41:38+00:00 Prince Ezenwa Ndubueze Onyemaechi Ijeoma Madubuike Igwe Emmanuel Okorie Nwosu Lorrita Chimluru <p><strong>BACKGROUND</strong>: According to Adolescents Human Immune Deficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) screening policy in Nigeria, all adolescents attending health facilities—including inpatient and outpatient clinics such as general outpatient, Sexually Transmitted Infection, family planning, tuberculosis, and surgical outpatient should be screened on each visit. Early detection of the virus enables early initiation of treatment and this is known to improve the outcome of treatment and quality of life. Adolescents are at high risk of contracting HIV/AIDS and as such should embrace HIV screening. Despite high HIV incidence rate, and prevalence of AIDS-associated mortality among adolescents, screening uptake among this age group has remained low. This low HIV<br>screening uptake suggests the presence of barriers limiting testing among this age group. This study seeks to assess the barriers to HIV screening among adolescents.<br><strong>OBJECTIVE</strong>: To assess the barriers to HIV screening among adolescents in Girls’ Secondary School Abayi, Aba.<br><strong>MATERIALS AND METHODS</strong>: A descriptive-cross sectional study was conducted among students of Girls’ Secondary School Abayi. A semi-structured questionnaire was used to obtain data from adolescents within the ages of 10-19 years. The data was then presented using tables and figures.<br><strong>RESULTS</strong>: In this study, only 6.7% of the adolescents have done HIV counseling and testing at least once. The following were identified as barriers to HIV screening; not knowing where the tests were done [18.6%,] cannot tell their parents to take them to a screening center [18.3%], screening center was far from home [6.2%], could not afford the transportation fee [4.2%], had no reason [52.7%]. The following were the reasons why they would not do HIV screening<br>if an opportunity was provided; fear of result outcome [23.5%], shame of being judged by the screening provider [11.1%], fear of being discriminated if result turned out positive [14.4%], anxiety of awaiting result [10.65%], had no reason [40.3%].<br><strong>CONCLUSION</strong>: Fear of a positive result, stigmatization, and poor awareness were the major barriers to HIV screening among adolescents. Until stigmatization is reduced to the barest minimum by providing more knowledge and a supportive environment where learners can feel they have adequate support, creating more awareness on HIV screening will not be enough to increase HIV counseling and testing uptake.</p> 2022-05-19T00:00:00+00:00 Copyright (c) Association between HIV infection, sociodemographic characteristics and depression in caregivers of HIV infected children in Enugu, South-East, Nigeria. 2022-05-19T07:46:45+00:00 Ikechukwu F. Ogbonna Ngozi C. Ojinnaka Anthony N. Ikefuna Ifeoma J. Emodi <p><strong>Background</strong>: In the presence of certain factors, HIV infection in children increases the burden of depression in their caregivers. This necessitated the need for this study which aimed to determine the factors that are associated with depression in the caregivers of HIVinfected children.<br><strong>Methods</strong>: A comparative hospital-based study of 352 study participants comprising two groups. The first group was the subjects consisting of 176 caregivers of HIV-infected children and the second was the control consisting of 176 caregivers of HIV negative children. Having met the inclusion criteria, these study participants were screened for HIV infection, their sociodemographic characteristics were obtained and depression in them was assessed using Zung self-rating depression scale (SDS). The essence was to determine the factors that were significantly associated with depression in the subjects.<br><strong>Results</strong>: Forty-three (24.4%) and 133 (75.6%) of the subjects were males and females respectively while 47 (26.7%) and 129 (73.3%) of the control were males and females respectively. Seventy-six (43.2%) of the subjects and 12 (6.8%) of the control group had SDS scores in the depression range and this difference was significant (2 = 62.06, df = 1, p &lt; 0.001). The factors that were significantly associated with depression in the subjects were the age of the HIV-infected children (p = 0.023, OR = 2.28), caregiver’s sex (p = 0.003, OR = 3.25), socioeconomic status (p &lt; 0.001, OR = 4.00), marital status (p &lt; 0.001, OR = 2.18), type of caregivers (p = 0.028, OR = 2.78), spouse support (p = 0.019, OR = 2.08).<br><strong>Conclusion</strong>: There is a high burden of depression among caregivers of HIV-infected children and depression in them is significantly associated with caring for a preadolescent HIVinfected child, female caregivers, lower socioeconomic status, death of a spouse, being a biologic caregiver and lack of spouse support.</p> 2022-05-19T00:00:00+00:00 Copyright (c)