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Journal of Pharmaceutical and Allied Sciences

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Studies on wound healing properties of Crateva religiosa leaf extract

U Ajali, KM Ezealisiji, EO Onuoha

Abstract


Dried leaves of Crateva religiosa were extracted with methanol using a soxhlet extractor. The classes of phytocompounds present in the extract were determined and the LD50  estimated in mice intraperitoneally. The extraction gave a yield of 14.6%. Alkaloids, carbohydrates, tannins, flavonoids, resins, proteins, oils, steroids and terpenoids were present. The extract had wound healing activity that was superior to that of penicillin. The faces of wound treated with the extract dried faster indicating that the extract had extrawound healing mechanism when compared to that of penicillin.

Keywords: Creteva religiosa, wound healing, phytochemisty, LD50

Journal of Pharmaceutical and Allied Sciences, Vol. 7 No. 4 (2010)



http://dx.doi.org/10.4314/jophas.v7i4.63457
AJOL African Journals Online