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Preliminary studies of some pharmacological properties of <i> Croton zambesicus</i>


Jude Okokon
Nnoye Nwajuaku
Aniekan Udokpoh

Abstract

The ethanolic leaf extract of Croton zambesicus was investigated for pharmacological properties against egg white-induced acute inflammation, acetic acid induced writhing and yeast induced fever in rats. The extract (100-200mg/kg) showed a dose – dependent anti-inflammatory, analgesic, and antipyretic activities. These activities were lower than that of the standard drug (Aspirin, 100mg/kg). The leaf extract possess anti-inflammatory, analgesic and antipyretic properties which can be exploited in health care.

Keywords: Croton zambesicus, anti-inflammatory analgesic, antipyretic

Journal of Pharmacy & Bioresources Vol. 2(2) 2005: 75-79

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eISSN: 0189-8442