Article Sidebar
Article Details
Copyright of articles published shall reside exclusively with the Faculty of Pharmaceutical Sciences, University of Jos.
DECLARATION & COPYRIGHT TRANSFER
I/We the undersigned author(s) of article entitled
…………………………………………………………………………………………………………………
…………………………………………………………………………………………………………………
Declare as follows:
- The manuscript submitted to Journal of Pharmacy & Bioresources is original and has not been and will be published, whole or in part, in print or electronic format, in any other journal. It is also not being currently considered for publication in any journal.
- The submitted manuscript is a joint decision of all the coauthors.
- Each author has participated sufficiently in the work to warrant his or her inclusion in the list of authors. To this end, each author takes responsibility for appropriate portions of the manuscript.
- Authors have obtained necessary approval to carry out the experiments on animals and human subjects. Approval certificates will be furnished, if required by publishers or editors of the journal.
- Authors do not have any conflict of interest (financial or otherwise) other than those declared.
- If the manuscript is accepted for publication, the authors transfer and assign copyright of the article referenced above to Journal of Pharmacy and Bioresources.
Name & Signature of authors
1. 2.
- 4.
- 6.
- 8.
Corresponding authors name address, affiliation and email:
Main Article Content
Synthesis of dehydrodipeptides as potential suicide substrates for D, D-peptidases
Abstract
The synthesis of the dehydrodipeptide phenoxyacyl dehydroserine–D–alanine to act as a potential suicide substrate for D, D-peptidase is presented. Starting with the hydrochloride of serine methyl ester, this was chemically transformed to the key phenoxyacyl-β–chloro Ala Ala which was dehydrohalogenated to the desired dehydrodipeptide.
Keywords: Suicide substrate, Phenoxyacyldehydrodipeptide, D, D-Peptidases
