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Journal of Pharmacy & Bioresources

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Antifungal evaluation of shell pyrolysates of oil palm (Elaeis guineensis Jacy) and coconut (Cocos nucifera L.)

Buniyamin A. Ayinde, Godwin Josephs, Michael Malomo, Lawrence Okoh, Abdul Ganiy Badmus, Nabeel A. Adeyemi

Abstract


The medicinal values of oil palm and coconut shells are not much known in herbal medicine and the two mostly constitute waste products. The antifungal effects of steam-distilled pyrolysates obtained from the two shells and the respective organic solvent fractions were evaluated against human pathogenic fungi Trichophyton megnini, T. rubrum and plant pathogenic fungi namely Penicillium, Aspergillus, Fusarium, Trichoderma and Collectotrichum at concentrations of 0.5-1.5mL. The two pyrolysates completely inhibited the growth of the organisms at 1-1.5mL whereas the growth inhibitory effects of the chloroform and ethyl acetate fractions were observed at 0.5 mL. The MICs of both fractions range between 0.06-0.08 mL for almost all the microorganism. The pyrolysates, chloroform and ethyl acetate fractions showed promising antifungal activities.

Keywords: Antifungal; Coconut shell; Oil palm shell; Pyrolysates




http://dx.doi.org/10.4314/jpb.v13i2.13
AJOL African Journals Online