Quality assessment of some brands of Ciprofloxacin tablets on sale in Abuja, Nigeria
AbstractThe quality of the various brands of ciprofloxacin tablets in circulation within Abuja, the Federal Capital City of Nigeria, was assessed. Spectrophotometric evaluation showed that all the brands contained a chemical equivalent of ciprofloxacin within the limits of the official specification. However their antimicrobial activity as indicated by the zone of inhibition was less than that of the reference standard. Three of the ten samples tested failed the disintegration and dissolution tests as specified by the British Pharmacopoeia for film coated tablets.
Key words: Ciprofloxacin; Quality assessment; Spectrophotometric evaluation; Microbial potency
Journal of Pharmacy and Bioresources Vol. 2 (1) 2004: 49-54