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Isolation and characterization of a flavonoid from, and antimicrobial evaluation of <i>Palisota hirsuta</i>
Abstract
The leaves and root bark of Palisota hirsuta were subjected to phytochemical studies in order to validate the ethnomedicinal claim of the plant. Evaluation of the extracts against some microorganisms was also carried out. The results of the study revealed significant antibacterial activity of the leaf against Gram-positive organisms with no activity against Gram-negative organisms. There was however absence of activity with the root part of the plant. The phytochemical studies of the bioactive leaf extract led to the isolation and characterization of a flavonoid compound. The ethnomedicinal use of the plant as remedy against bacterial infections was justified.
Keywords: Palisota hirsute; Commelinaceae; Antibacterial activity; Flavonoid
