In vitro antibacterial activities of the seed extract ofPicralima nitida

  • Aniekan E Udokpoh
  • Peace ME Ubulom
  • Arnold C Igboasoiyi
  • Sinyefori A Brown
  • Edoho J Edoho
  • Ekaete I Akpabio
DOI: 10.4314/jpb.v6i2.63332

Abstract

The in vitro antibacterial activities of Picralima nitida seed extracts were studied against selected pathogenic bacteria. Seeds were extracted using ethanol, methanol and water. Among the three solvents used, seed extracts of ethanol and methanol were more effective against pathogenic bacteria, where the minimum inhibitory concentration (MIC) ranged between 31.0mg/l to 75.0mg/l and inhibition zone diameter (IZD) of between 11mm to 19mm. All the extracts were ineffective against P. aeruginosa and S. typhi. The antimicrobial activities of the seeds of this indigenous medicinal plant are  discussed in this paper.

Keywords: Antibacterial activity, Picralima nitida, Seeds

Journal of Pharmacy and Bioresources, Vol. 6 no. 2, pp. 38-42 (September 2009)

Author Biographies

Aniekan E Udokpoh
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Peace ME Ubulom
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Arnold C Igboasoiyi
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Sinyefori A Brown
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Edoho J Edoho
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Ekaete I Akpabio
Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria
Issue
Vol. 6 No. 2 (2009)
Section
Articles

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