Anti-ulcerogenic activity of ethanolic leaf extract of Heinsia crinata

  • JE Okokon
  • EO Etebong
  • EE Umoh
  • GE Essien
Keywords: Heinsia crinata, Anti-ulcer, Vegetable


The anti-ulcer activity of Heinsia crinata, a vegetable, used ethnomedicinally in the treatment of ulcer was evaluated to confirm this claim.The crude ethanolic leaf extract (450 – 1350mg/kg) was investigated against indomethacin, ethanol and histamine – induced ulcer models in rats.The crude leaf extract demonstrated significant (p<0.001) inhibition of ulcer produced by the ulcerogens used; indomethacin, ethanol and histamine.The results of this work confirms the folkloric use of this plant in the treatment of ulcer.

Keywords: Heinsia crinata; Anti-ulcer; Vegetable


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eISSN: 0189-8442