Bone Morphogenetic Protein 3 (BMP3) Gene Variation in some Livestock Animals

Abstract

Variation in Bone Morphogenetic Protein 3 (BMP3) genes in some selected  livestock animals was assessed using sequences downloaded from the GenBank  (https://www.ncbi.nlm.nih.gov/genbank/). The analysis was carried out in 36  pair-wise comparisons where averages of 1277.780 sites were analyzed. Analysis at individual sites revealed a nucleotide diversity (Pi) of 0.566. Theta-W per  sequence was 611.817 while Theta-W per site was 0.387. Gene flow estimates using haplotype data information showed Gst value as 0.013 while gene flow  estimates using sequence data information revealed, Delta St of 0.131, and Gamma St of 0.270. Furthermore, Nst value was 0.00618 and Fst, -0.019. The highest  genetic distance at the Bone Morphogenetic Protein 3 (BMP3) gene loci between the organisms under this study was that between chicken and sheep (85.00) and the lowest distance were seen between cattle and sheep (9.66). The dendogram  revealed two major clusters. Chicken and goats were closely related at the Bone Morphogenetic Protein 3 (BMP3) gene locus and both were separated from the other cluster which comprises of cattle, sheep, and rabbit. This study has revealed vital information that will help in better understanding the relatedness in the functions of the bone morphogenetic protein 3 genes in these selected livestock animals.

Keywords: Bone Morphogenetic Protein 3, gene, livestock