Nigerian Journal of Clinical Practice

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Typhoid glomerulonephritis and intestinal perforation in a Nigerian child

OI Odetunde, OU Ezenwosu, OA Odetunde, JC Azubuike


The number of children with renal complications following salmonella infection cannot be precisely defined in the sub-Saharan Africa due to scarcity of reliable data. We report a 3-year-old boy with glomerulonephritis secondary to typhoid infection and later intestinal perforation. He  presented with fever, generalized body swelling, oliguria, coke-colored
urine and hypertension and had been managed 3 weeks earlier for typhoid fever in a private hospital. Laboratory investigations showed proteinuria, hematuria with red cell casturia and azotemia. Abdominal X-ray done was suggestive of typhoid intestinal perforation that was confirmed at   exploratory laparotomy. He was managed aggressively with antibiotics and was discharged on the 25th day of admission. To the best of our   knowledge, this is the first documented case report of acute   glomerulonephritis and intestinal perforation as co.complications of salmonella infection in Nigeria.

Key words: Acute glomerulonephritis, intestinal perforation, Nigeria, typhoid fever
AJOL African Journals Online