PROMOTING ACCESS TO AFRICAN RESEARCH

Nigerian Journal of Clinical Practice

Log in or Register to get access to full text downloads.

Remember me or Register



Anthropometric characteristics of offspring of Nigerian Type 2 Diabetics

JO Adeleye, FM Abbiyesuku

Abstract


Objectives: Type 2 diabetes mellitus (DM) has a strong genetic component. Overall obesity and central obesity have strong associations with insulin resistance, which is a major factor in the development of impaired glucose tolerance (IGT) and Type 2 DM. The impact of a parental history of Type 2DM on anthropometric measurements known to govern glucose tolerance was examined in this study.

Materials and Methods: Weight, height, body mass index, waist circumference, hip circumference and waist-hip ratio were measured in 52 offspring of Nigerian Type 2 diabetic patients and compared with 50 control subjects who had a similar distribution of age, sex and socio-economic class.

Results: Offspring of diabetics had a significantly higher mean (SD) (i) weight (69.9(15.1)kg vs 63.8 (63.8(112)kg;p=0.024); (ii) body mass index (25.0(4.9)kg/m2 vs 23.0 (3.0)kg/m2;p=0.013;) (iii) Waist circumference (82.3(12.2) cm vs 77.2 (8.3) cm; P=0.014); (iv) hip circumference (99.0 (11.4) cm vs. 93.0 (7.2) cm; p=0.005). The waist-hip ration for both groups of subjects did not differ significantly (0.83(0.06) versus 0.82 (0.05);p=0.52).

Conclusion: These results suggest that a parental history of Type 2 DM influences body fat and its distribution resulting in greater degrees of generalized and central/abdominal fat, implying a greater risk of developing Type 2 DM in view of the relationship between body fat distribution and insulin resistance. Long-term prospective studies are needed to define anthropometric indices predictive of the development of Type 2 DM, as well as its relation to insulin sensitivity, amongst Nigerians.
KEY WORDS:- Type 2 diabetic parents, offspring, Anthropometry
Nigerian Journal of Clinical Practice Vol.5(2) 2002: 75-80



AJOL African Journals Online