Nigerian Journal of Clinical Practice

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Mature cystic teratomas: Relationship between histopathological contents and clinical features

M Nacar, Z Ozsoy, N Aliyev, D Koseoglu


Aims: The aim of this study was to evaluate the relationship between pathological findings and clinical features in patients with ovarian mature cystic teratomas (MCTs).
Materials and Methods: We reviewed and compared the demographic and clinical features of 32 patients confirmed pathologically as having MCT at a university hospital from 2009 to 2014, with MCT contents such as skin, hair, sebum, and cartilage.
Results: The mean age of the patients was 33.7 ± 13.4 years. The mean tumor diameter was 7.1 ± 3.3 cm (range: 2-15 cm). The mean serum CA‑19.9 level was 37.5 ± 79.5 IU/ml and the mean serum CA‑125 level was 29.1 ± 33.0 IU/ml. The postmenopausal and pregnancy status rates of participants were 18.8, and 15.6%, respectively. The mean age, postmenopausal and pregnancy status, tumor size, symptoms related to MCT and laterality of the tumor did not differ among the patients according to the MCT contents.
Conclusions: Our findings suggest no relationship between the clinical features and histopathological contents of MCTs.

Key words: Histopathological contents, mature cystic teratoma, ovarian, tumor
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