An Innovative Application of Pre-Medicated Collagen Sponges with Regenerative Biomaterials for Management of an Infected Extraction Socket: A Case Report

Abstract

Localized infection of the extraction socket can compromise bone quality and quantity within the socket and bone support for the adjacent dentition.  These events can preclude immediate rehabilitative interventions, such as implant placement, and increase the technical sensitivity of guided bone  regeneration procedures for successful tissue and bone gain. The use of local scaffolds containing effective antimicrobial agents may suppress local  infection and facilitate the regenerative process related to the introduced bone graft particles and barrier collagen membrane. In this case report, pre- medicated collagen sponges containing chlorhexidine and metronidazole were used in conjunction with a bone graft and collagen membrane for guided  tissue and bone regeneration, which was followed by delayed implant placement with 2 years of follow-up evaluations.