Nigerian Journal of Clinical Practice

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Prevalence of dyslipidemia among adult diabetic patients with overt diabetic nephropathy in Anambra state South-East Nigeria

NN Jisieike-Onuigbo, EI Unuigbe, OA Kalu, CO Oguejiofor, PC Onuigbo


Background: Dyslipidemia has been identified as a risk factor for the development and progression of diabetic renal disease.
Objective: This study was done to determine the prevalence of dyslipidemia among diabetic patients with overt nephropathy.
Materials and Methods: A total of 72 diabetic patients with overt diabetic nephropathy and 36 age- and sex-matched normoalbuminuric diabetic patients were studied. Their fasting lipid profile, fasting blood sugar, and renal function tests were evaluated.
Results: Total serum cholesterol and serum triglycerides were significantly higher in patients with overt diabetic nephropathy compared to the controls; 66.7% and 62.5% versus 36.1% and 30.6%, respectively (P = 0.003 and 0.002, respectively).
Conclusions: Diabetic patients with overt diabetic nephropathy have significant dyslipidemia and aggressive lipid lowering in these patients may retard their progression to end-stage renal disease.
AJOL African Journals Online