Nigerian Journal of Clinical Practice

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Effects of the topical hemostatic agent Ankaferd Blood Stopper on the incidence of alveolar osteitis after surgical removal of an impacted mandibular third molar

M Tek, I Akkas, O Toptas, F Ozan, I Sener, C Bereket


Background: Alveolar osteitis (AO) is a commonly seen post‑operative complication during the wound‑healing period after permanent tooth extraction or surgical removal of impacted third molar teeth.
Objectives: The aim of this clinical study was to evaluate the effects of administration of the topical hemostatic agent Ankaferd Blood Stopper (ABS) into the socket on AO formation after impacted mandibular third molar extraction.
Patients and Methods: Bilaterally, 100 half‑impacted mandibular third molars were extracted in 50 patients. Then, 1.0 mL ABS was administered to achieve hemostasis in one half of the sockets and as a control, the other half was irrigated with 1.0 mL physiological serum after surgery.
Results: There was no statistically significant difference in terms of AO formation (P > 0.05) between the extraction sites. However, the postoperative pain in ABS administration sites was higher than in the other sites for the first 2 days after surgery (P < 0.05).
Conclusions: The results showed that ABS administration did not increase the incidence of AO formation. Thus, ABS can be used safely for hemostasis after impacted mandibular third molar surgery.

Key words: Alveolar osteitis, Ankaferd Blood Stopper, hemostasis, third molar
AJOL African Journals Online