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Antibiotic Susceptibility Pattern and Beta-Lactamase Production of Strains of <i>Campylobacter</i> Species Isolated in Ile-Ife, Nigeria
Abstract
Nigerian Journal of Biomedical Sciences Vol.3(2) 2004:
The study was to determine the antibiotic susceptibility patterns and beta-lactamase production of Campylobacter jejuni/coli isolates obtained from stool specimens from children with diarrhoea at the Obafemi Awolowo University Teaching Hospital Complex (O.A.U.T.H.C.), Ile-Ife. Thirty strains of Campylabacter jejuni/coli were isolated from children with diarrhoea in the clinical laboratory of the department of Medical Microbiology and Parasitology of O.A.U.T.H.C. The antimicrobial susceptibility test was carried out according to the method described by Bauer et al, 1966. All isolates were tested for evidence of beta-lactamase activity by the starch paper technique (Odugbemi et al 1977). All isolates tested were sensitive to erythromycin, gentamicin, tetracycline and ciprofloxacin whereas only one strain was sensitive to cotrimoxazole. None of the isolates produced beta-lactamase. In this environment, the clinical use of erythromycin, tetracycline, gentamicin and ciprofloxacin is recommended for the treatment of Campylobacter enteritis.
KEY WORDS: Campylobacter jejuni/coli; beta-lactamase; antibiotics; susceptibility.
Nigerian Journal of Biomedical Sciences Vol.3(2) 2004: 61-64
The study was to determine the antibiotic susceptibility patterns and beta-lactamase production of Campylobacter jejuni/coli isolates obtained from stool specimens from children with diarrhoea at the Obafemi Awolowo University Teaching Hospital Complex (O.A.U.T.H.C.), Ile-Ife. Thirty strains of Campylabacter jejuni/coli were isolated from children with diarrhoea in the clinical laboratory of the department of Medical Microbiology and Parasitology of O.A.U.T.H.C. The antimicrobial susceptibility test was carried out according to the method described by Bauer et al, 1966. All isolates were tested for evidence of beta-lactamase activity by the starch paper technique (Odugbemi et al 1977). All isolates tested were sensitive to erythromycin, gentamicin, tetracycline and ciprofloxacin whereas only one strain was sensitive to cotrimoxazole. None of the isolates produced beta-lactamase. In this environment, the clinical use of erythromycin, tetracycline, gentamicin and ciprofloxacin is recommended for the treatment of Campylobacter enteritis.
KEY WORDS: Campylobacter jejuni/coli; beta-lactamase; antibiotics; susceptibility.
Nigerian Journal of Biomedical Sciences Vol.3(2) 2004: 61-64
