Hyperemesis Gravidarum as a Cause of Pregnancy-related Acute Kidney Injury: A Case Report from Ile-Ife, South West Nigeria

  • Michael Sylvester Archibong
  • Olumide Adedotun Adeniyi
  • Fayowole Olabanji Nana
  • Olaniyi Joseph Olayemi
Keywords: Acute kidney injury, hyperemesis gravidarum, fluid therapy


Hyperemesis gravidarum (HG) complicated by acute kidney injury (AKI) is not commonly encountered in practice. Despite the extreme rarity of HG as a cause of AKI, health‑care providers should be aware of the likelihood of such a complication. The aim of the study was  to report a case of HG complicated by AKI. A 35‑year‑old G2P1+0 (one alive) female presented with progressively worsening nausea and  vomiting with associated weight loss and reduced urinary output at the gestational age of 17 weeks. Serum creatinine and urea values at  presentation were 883 µmol/L and 56 mmol/L, respectively. She, however, responded to intravenous fluid  therapy/replacement with subsequent normalization of serum urea and creatinine values and restoration of renal function. AKI can be a complication of HG. Individualized care of affected women will improve the prognosis.

Keywords: Acute kidney injury, hyperemesis gravidarum, fluid therapy


Journal Identifiers

eISSN: 2667-0526
print ISSN: 1115-2613