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Antiimplantation And Abortifacient Activities Of <i>Oxalis corniculata</i> In Albino Rats

K Sharangouda
S B Patil


Petroleum ether and ethanol extracts of the whole plant of Oxalis corniculata were administered orally at the dose level of 100 and 200 mg/kg body weight from day 1 to 7 of pregnancy to evaluate the antiimplantation activity. Though all the treated groups showed significant antiimplantation activity when laparotomised on day 10, it was maximum (76.42%) with the high dose of petroleum ether extract. Upon withdrawal of the treatments the rats which retained the implantation continued pregnancy. The pregnant rats which received the treatment from day 8 to 14 of pregnancy showed abortifacient activity and it was maximum (78.55%) with high dose of petroleum ether extract.

Keywords: Oxalis corniculata; Oxalidaceae; Albino rat; Antiimplantation; Abortifacient; Pregnancy

Nigerian Journal of Natural Products and Medicine Vol. 11 2007 pp. 58-60

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eISSN: 1118-6267