Article Sidebar
Published:
Oct 24, 2005Keywords:
sickle cell retinopathy pattern of presentation genotype
Article Details
Issue
Section
Articles
The entire contents of the Nigerian Journal of Ophthalmology are protected under Indian and international copyrights. The Journal, however, grants to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, perform and display the work publicly and to make and distribute derivative works in any digital medium for any reasonable non-commercial purpose, subject to proper attribution of authorship and ownership of the rights. The journal also grants the right to make small numbers of printed copies for their personal non-commercial use under Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License.
Main Article Content
Pattern of presentations seen in sickle cell retinopathy patients at eye foundation hospital Lagos, Nigeria
Abstract
Objective: To describe the pattern of presentation of sickle cell retinopathy patients who presented at the Eye Foundation Hospital Lagos, Nigeria between January 2002 and March 2003.
Materials and Methods: The medical records of 27 patients who presented at the Eye Foundation Hospital with retinal changes due to sickle cell disease within a 15-month period were reviewed retrospectively.
Results: A total of 27 patients were evaluated, 67% were male while 33% were female. The mean age at presentation was 36.18 years with female patients tending to present earlier than male patients.The most common complaint at presentation was a sudden drop in vision seen in 63% of the patients evaluated. The dominant genotype among the patients was SC with 81.5%; 7.4% were SS and 11.1% were AS. The duration from onset of symptoms to presentation was evaluated. The median duration at presentation was greater than 12 weeks after onset of symptoms; 85% of patients presenting had proliferative retinal changes. Proliferative sickle retinopathy (PSR) changes were classified according to Goldbergs classification of 1971. Stage 4 PSR was the most common stage seen, occurring in 48% of patients.
Conclusion: Sickle cell retinopathy patients seen at the Eye Foundation Hospital generally presented after 12 weeks of onset of sudden drop in vision. They were mostly in the SC genotype group and mostly had stage 4 proliferative retinopathy according to Goldbergs classification.
Keywords: sickle cell retinopathy, pattern of presentation, genotype
Nigerian Journal of Ophthalmology Vol. 13 (1) 2005: 17-20
Materials and Methods: The medical records of 27 patients who presented at the Eye Foundation Hospital with retinal changes due to sickle cell disease within a 15-month period were reviewed retrospectively.
Results: A total of 27 patients were evaluated, 67% were male while 33% were female. The mean age at presentation was 36.18 years with female patients tending to present earlier than male patients.The most common complaint at presentation was a sudden drop in vision seen in 63% of the patients evaluated. The dominant genotype among the patients was SC with 81.5%; 7.4% were SS and 11.1% were AS. The duration from onset of symptoms to presentation was evaluated. The median duration at presentation was greater than 12 weeks after onset of symptoms; 85% of patients presenting had proliferative retinal changes. Proliferative sickle retinopathy (PSR) changes were classified according to Goldbergs classification of 1971. Stage 4 PSR was the most common stage seen, occurring in 48% of patients.
Conclusion: Sickle cell retinopathy patients seen at the Eye Foundation Hospital generally presented after 12 weeks of onset of sudden drop in vision. They were mostly in the SC genotype group and mostly had stage 4 proliferative retinopathy according to Goldbergs classification.
Keywords: sickle cell retinopathy, pattern of presentation, genotype
Nigerian Journal of Ophthalmology Vol. 13 (1) 2005: 17-20
